Risk-conscious enterprises across the globe have been reluctant to embrace the public cloud model. For many, compliance requirements are the source of the reluctance. For others, concerns about ceding control of their data to a cloud service provider, without the cloud service provider accepting liability for customer data, is the major hurdle. Conforming to data residency regulations, when implementing a distributed services model, present a further complication. Even as these challenges to adoption loom large, the economics and productivity benefits of cloud-based services remain compelling. For these organizations to make the transition to the cloud, a range of elements must be in place, including continuous monitoring of the cloud service provider’s data center, enforcement of appropriate service level agreements, data classification and definition of internal processes to manage cloud-based services. Encryption in use is a critical piece of this puzzle, since it provides a mechanism for the enterprise to extend their boundary of control to their data stored and processed within the cloud service provider’s environment. However, not all encryption in use is created equally, secure, and a generic. A one size fits all approach is likely to fall short in providing a balance between security and functionality.